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AG Scientific Fumagillin, 1 MG
AG Scientific Fumagillin (1 MG) is an antimicrobial agent isolated from Aspergillus fumigatus. It is a specific inhibitor of methionine aminopeptidase-2 (MetAP-2) by covalently binding histidine residue of it (Additional S&H Or Hazmat Fees May Apply) - AG
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$67.53
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| NETA PART: | RPI-F-1028-1MG |
| MFG.PART: | F-1028-1MG |
| UNSPSC: | 51102800 |
| Manufacturer: | AG Scientific |
AG Scientific
Fumagillin is used as an antimicrobial agent from Aspergillus fumigatus. It is a specific inhibitor of methionine aminopeptidase-2 (MetAP-2) by covalently binding histidine residue of it. It is reported that this fungal metabolite suppresses angiogenesis and proliferation of endothelial cells.
It is a potent treatment of intestinal microsporidiosis in immunocompromised patients. It is reported that a derivative of fumagillin, AGM-1470, is related to angioinhibitory action by suppressing of mRNA expression of specific members of CDKs and cyclins and activation of CDC2 and CDK2 kinases in endothelial cells.
| SKU | RPI-F-1028-1MG |
|---|---|
| Supplier Part Number | F-1028-1MG |
| UM | EA |
| UNSPSC | 51102800 |
| Manufacturer | AG Scientific |
| MSDS URL | https://agscientific.com/system/product_documents/F-1028%2C%20Fumagillin%2C%20SDS%202022_r01_2.pdf |
| Temperature | -20°C |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United Kingdom |
| ProductLine | AG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 5.00 |
| Lead Time | 5 Business Days |
| Hazardous | N |
| CAS Number | 23110-15-8 |