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Cell Signaling Cytochrome C (136f3) Rabbit mAb
Cell Signaling Cytochrome C (136f3) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$139.00
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$139.00
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| NETA PART: | CSIG-4280T |
| MFG.PART: | 4280T |
| UNSPSC: | 12352202 |
| Manufacturer: | Cell Signaling |
| Size | 20 µl |
| Reactivity | H M R Hm Mk |
| Sensitivity | Endogenous |
| Molecular Weight (kDa) | 14 |
| Source/Isotype | Rabbit IgG |
| Application/Dilution | {Western Blotting: 1:1000, Immunohistochemistry (Paraffin): 1:50 - 1:200} |
| Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | Cytochrome c (136F3) Rabbit mAb detects endogenous levels of total cytochrome c protein. |
| Species Reactivity | Human, Mouse, Rat, Hamster, Monkey |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro72 of human cytochrome c protein. |
| Background | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3). |
| SKU | CSIG-4280T |
|---|---|
| Supplier Part Number | 4280T |
| UM | UNIT |
| UNSPSC | 12352202 |
| Manufacturer | Cell Signaling |
| MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
| Temperature | -20C |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 5 Business Days |