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Cayman Daidzein; Purity- Greater Than Or Equal To 95%; Size- 100
NETA PART: | CAYM-10005166-100 |
MFG.PART: | 10005166-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Daidzein is an isoflavone phytoestrogenic compound that has been found in soybeans and other legumes. It binds to estrogen receptor β (ERβ; Ki = 2.8 µM) but not ERα at concentrations up to 1 mM. It is estrogenic in vitro, increasing gene transcription mediated by the estrogen response element (ERE) in a reporter assay in an ERβ-dependent manner (EC50 = 2.8 µM for MCF-7 cells expressing ERβ). Daidzein is an inhibitor of carbonic anhydrase (CA) that is selective for carbonic CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively). It reduces tumor growth in a PC3 prostate cancer mouse orthotopic model when administered at a dose of 50 mg/kg per day and potentiates the effects of radiation therapy.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 10 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:10): 0.15 mg/ml
- Ethanol: 0.1 mg/ml
Shipping & Storage Information
SKU | CAYM-10005166-100 |
---|---|
Supplier Part Number | 10005166-100 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10005166m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 100 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 486-66-8 |