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Cayman 1,2-Dioctanoyl Pc; Purity- Greater Than Or Equal To 98%; S
List Price
$16.00
Your Price
$16.00
Cayman 1,2-Dioctanoyl Pc; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-10009874-5
MFG.PART:
10009874-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Fructose-1,6-bisphosphatase-1 (FBPase-1) is an enzyme that catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate, which is one of the rate-limiting steps in gluconeogenesis. Excess hepatic FBPase-1 activity contributes to hyperglycemia in patients. Thus, the development of specific FBPase-1 inhibitors is of great clinical interest for the treatment of patients with type 2 diabetes. FBPase-1 inhibitor is a cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity with an IC50 value of 3.4 µM (Ki = 1.1 µM) by competing at the AMP allosteric binding site., It has been shown to block glucose production in rat hepatoma cells that are starved of nutrients with an IC50 value of 6.6 µM.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,5-dichloro-
CAS Number
883973-99-7
Synonyms
- F1,6BPase-1 Inhibitor
- FBP1 Inhibitor
- FBPase-1 Inhibitor
Molecular Formula
C13H7Cl3N2O3S
Formula Weight
377.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml
- DMSO: 14 mg/ml
λmax
204, 287 nm
SMILES
ClC1=CC=C2C(N=C(NS(C3=C(Cl)C=CC(Cl)=C3)(=O)=O)O2)=C1
InChi Code
InChI=1S/C13H7Cl3N2O3S/c14-7-2-4-11-10(5-7)17-13(21-11)18-22(19,20)12-6-8(15)1-3-9(12)16/h1-6H,(H,17,18)
InChi Key
JCXZHFCBNFFHRC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10009874-5 |
|---|---|
| Supplier Part Number | 10009874-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 19191-91-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |