AG Scientific 5-Methylcytidine, 1 G

5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine.It has been used in epigenetics research, especially in studies involving DNA methylation processes including genomic imprinting and the control of gene expression and differentiation.

The presence of 5-methylcytidinein tRNA and rRNA molecules of a wide variety of organisms was first observed more than 40 years ago.Recent studies in eukaryotes have shown that mRNA modifications such as RNA-editing (conversion of an adenosine base to inosine), N6-adenine methylation (m⁶A), and 5-methylcytidinecan change the coding sequence, alter splicing patterns, or change RNA stability.

5-methylcytidineis a modification that occurs both on DNA and RNA. In eukaryotes, this DNA modification has been extensively studied over the past years, and has been found to play a crucial role in genomic imprinting, X-chromosome inactivation, and suppression of repetitive elements.