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Cayman S107
List Price
$565.00
Your Price
$565.00
Cayman S107 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-13253-50
MFG.PART:
13253-50
UNSPSC:
41116012
Manufacturer:
Cayman
Product Description
S107 is a stabilizer of the protein-protein interaction between ryanodine receptor 1 (RyR1) and FK-506 binding protein 1A (FKBP12).1,2 It stabilizes sarcoplasmic reticulum RyR1 channels by decreasing the dissociation of FKBP12 in isolated mouse muscle fibers.2 S107 (50 and 100 µM) also reduces neurite growth and length in isolated spinal cords from neonatal rats.3 Ex vivo, S107 reduces exercise-induced calcium leakage in mouse muscle fibers.1 S107 decreases muscle fatigue and increases treadmill running time in mice. It increases grip strength and reduces exercise-induced muscle damage in a dystrophin DMD-/- knockout mouse model of Duchenne muscular dystrophy.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3,4,5-
CAS Number
927871-76-9
Molecular Formula
C11H15NOS
Formula Weight
209.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 0.5 mg/ml
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
λmax
258, 292 nm
SMILES
COC1=CC=C(SCCN(C)C2)C2=C1
InChi Code
InChI=1S/C11H15NOS/c1-12-5-6-14-11-4-3-10(13-2)7-9(11)8-12/h3-4,7H,5-6,8H2,1-2H3
InChi Key
BGVCEGVSQDOGSB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13253-50 |
|---|---|
| Supplier Part Number | 13253-50 |
| UM | EA |
| UNSPSC | 41116012 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 927871-76-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |