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Cayman Lipoxygenase (potato) Screening Enzyme
List Price
$281.00
Your Price
$281.00
Cayman Lipoxygenase (potato) Screening Enzyme - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-60401-1
MFG.PART:
60401-1
UNSPSC:
12352204
Manufacturer:
Cayman


Product Description
LXS-196 is a PKC inhibitor (IC50s = 1.9 and 0.4 nM for PKCα and PKCθ, respectively). It is selective for PKCα and PKCθ over GSK3β (IC50 = 3,100 nM). It inhibits proliferation of TMD8 B cell lymphoma and 92.1 uveal melanoma cells (IC50s = 900 and 184 nM, respectively) but not SK-MEL-28 skin melanoma cells (IC50 = >10,000 nM).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-amino-N- [3-(4-amino- 4-methyl-1- piperidinyl)- 2-pyridinyl]- 6-[3-(tri fluoromethyl)- 2-pyridinyl]- 2-pyrazine carboxamide
CAS Number
1874276-76-2
Molecular Formula
C22H23F3N8O
Formula Weight
472.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/ml
- DMSO: 1 mg/ml
- DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
λmax
288, 375 nm
SMILES
O=C(C1=C(N)N=CC(C2=C(C(F)(F)F)C=CC=N2)=N1)NC3=NC=CC=C3N4CCC(C)(CC4)N
InChi Code
InChI=1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34)
InChi Key
XXJXHXJWQSCNPX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-60401-1 |
---|---|
Supplier Part Number | 60401-1 |
UM | EA |
UNSPSC | 12352204 |
Manufacturer | Cayman |
MSDS URL | Click here |
Temperature | -80 |
Refrigerated-Frozen | Frozen |
CountryOfOrigin | United States |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.000000 |
Lead Time | 2 |
Hazardous | N |
Energy Star | No |
Green | No |
Controlled | N |