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GenScript Tnf-Α, Mouse; 20ug
List Price
$180.00
Your Price
$180.00
GenScript Tnf-Α, Mouse20ug - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART:
GSCRPT-Z02774-20
MFG.PART:
Z02774-20
UNSPSC:
12352202
Manufacturer:
GenScript USA Inc
Product Introduction
| Species | Mouse | |
| Protein Construction | Expressed with an N-terminal Met.
| |
| Purity | > 98% as analyzed by SDS-PAGE > 98% as analyzed by HPLC | |
| Endotoxin Level | < 1 EU/μg of protein by LAL method | |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg in the presence of actinomycin D. | |
| Expression System | E. coli | |
| Theoretical Molecular Weight | 17.4 kDa | |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.2. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Tumor necrosis factor alpha (TNF-α) is produced by neutrophils, activated lymphocytes, macrophages, NK cells, LAK cells, astrocytes endothelial cells, smooth muscle cells and some transformed cells. Mouse TNF-α occurs as a membrane-anchored form. The naturally-occurring form of TNF-α is glycosylated, but non-glycosylated recombinant TNF-α has comparable biological activity. The biologically active native form of TNF-α is reportedly a trimer. Human and mouse TNF-α show approximately 79% homology at the amino acid level and crossreactivity between the two species. |
| Synonyms | TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; DIF; TNFA; TNFSF2 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z02774-20 |
|---|---|
| Supplier Part Number | Z02774-20 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |