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Millipore Anti-Peripherin-2 Antibody, Clone 6b10.1 Is A Highly Specific Mouse Monoclonal Antibody, That Targets Peripherin & Has Been Tested In Western Blotting & Ihc. - Mill (Additional S&H or Hazmat Fees May Apply)
Peripherin-2 (PRPH2) is also called Retinal degeneration slow protein (RDS) and Tetraspanin-22 (Tspan-22). Peripherin-2 is a critical factor in ocular disk morphogenesis and possibly functions as an adhesion molecule helping to stabilize and compact outer segment disks, to help maintain curvature of the rim. Peripherin-2 is expressed in the photoreceptors of the retina and in the rim of rod outer segment (ROS) disks. Peripherin-2 defects are found in different retinal diseases including cone-rod dystrophy, retinitis pigmentosa, and macular degeneration.
Product Information
Format
Purified
Presentation
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-Peripherin-2 Antibody, clone 6B10.1 is a highly specific mouse monoclonal antibody, that targets Peripherin & has been tested in western blotting & IHC.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Peripherin-2 in 10 µg of human retina tissue lysate. Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Peripherin-2 in human retina tissue.
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to the cytoplasmic domain of human Peripherin-2.
Epitope
Cytoplasmic domain
Clone
6B10.1
Host
Mouse
Isotype
IgG1κ
Species Reactivity
Mouse
Human
Rat
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_000313
Gene Symbol
PRPH2
PRPH
RDS
TSPAN22
Purification Method
Protein G Purified
UniProt Number
P23942
Molecular Weight
~35 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in mouse eye tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Peripherin-2 in 10 µg of mouse eye tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
