Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times with existing HPLC and UHPLC instrumentation.
Analyzing polar compounds using liquid chromatography has historically been a challenge due to poor retention, long equilibration times, low sensitivity, and the need to mitigate these problems with time-consuming sample derivatization or complex ion-pairing approaches. However, with the development of the Raptor Polar X column—a novel column that is specifically designed for the analysis of a broad range of polar compounds—scientists can avoid these problems. These new columns feature a unique phase chemistry that combines both HILIC and ion-exchange retention mechanisms on a single ligand. Because this ligand is bound to superficially porous particles, Raptor Polar X columns both reliably retain and efficiently separate a wide variety of polar analytes with simple mobile phase changes. By analyzing polar compounds on a column that provides purpose-built resolving power, you can avoid complex sample preparation procedures, save time and money, and reduce opportunities for error. Simplify the analysis of polar compounds with the resolving power of Raptor Polar X columns from Restek.
The Raptor Polar X column has been included in the Quick Polar Pesticides (QuPPe) compendium of methods published by the European Union Research Laboratory for Single Residue Methods (EURL-SRM) for the analysis of a variety of polar pesticides in food [1].
[1] M. Anastassiades, A.-K. Wachtler, D. I. Kolberg, E. Eichhorn, H. Marks, A. Benkenstein, S. Zechmann; D. Mack, C. Wildgrube, A. Barth, I. Sigalov, S. Görlich, D. Dörk, G. Cerchia, Quick method for the analysis of highly polar pesticides in food involving extraction with acidified methanol and LC - or ICMS/MS Measurement - I. Food of Plant Origin (QuPPe-PO-Method)–Version 12 (published on EURL-SRM website on July 23, 2021). https://www.eurl-pesticides.eu/docs/public/tmplt_article.asp?LabID=200&CntID=1115&Theme_ID=1&Pdf=False&Lang=EN
Pore Size: 90 Å
Particle: 2.7 µm superficially porous particle (SPP or “core-shell” particle) silica
Surface Area: 130 m2/g
End-Cap: Proprietary
Carbon Load: Proprietary
USP Phase Code: NA
Phase Category: Proprietary
Ligand Type: Proprietary
Recommended Usage:
pH Range: 2.0–8.0
Maximum Temperature: 60 °C
Maximum Pressure: 600 bar/8700 psi
Properties:
- Excellent resolution and separation of a wide variety of polar compounds.
- Combines HILIC and ion-exchange retention mechanisms together in a single ligand.
- Broadly applicable for polar compound analysis spanning different industries and methods.
Switch to a Raptor Polar X column when:
- You are analyzing neutral, acidic, basic, or permanently charged polar compounds.
- Performing LC-MS/MS analysis of polar compounds.
- You are struggling to retain or elute polar compounds and considering ion chromatography.
