GenScript Toxineraser™ Endotoxin Removal Kit; 1Kit

Name: GenScript Toxineraser™ Endotoxin Removal Kit; 1Kit
SKU: GSCRPT-L00338
Price: 126.00 USD

List Price $126.00 Your Price $126.00

GenScript Toxineraser™ Endotoxin Removal Kit - GSCRPT (Additional S&H or Hazmat Fees May Apply)

NETA PART: GSCRPT-L00338

MFG.PART: L00338

UNSPSC: 41105322

Manufacturer: GenScript USA Inc

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Overview

Product Description

Lipopolysaccharide (LPS) is a bacterial endotoxin, and a major constituent of the cell walls of gram- negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is the principal pathophysiological mediator by which bacteria can cause hypotension, organ failure, disseminated intravascular coagulation, and fatal shock in mammalian hosts. Removal of endotoxin from drugs, injectables, and other biological products is necessary but can also be very difficult.
GenScript’s ToxinEraser™ is an endototoxin removal resin of high efficiency. It is based on affinity matrix of modified polymyxin B (PMB), which allows highly efficient endotoxin removal. The final endotoxin level can be decreased to less than 0.1 EU/ml with repeated use of ToxinEraser™ endotoxin removal resin. Final removal efficiency may vary depending on the sample type/source.

Key Features

High stability and high removal efficiency
High binding capacity: > 2, 000, 000 EU / ml (CV)
Fast flow without any constant speed pump
Reusable up to five times if properly regenerated
Ready-to-use reagents and materials, such as equilibration buffer, collection tubes, etc.

Product Introduction

Kit Contents

Kit Contents （Cat. No.:L00338）	PK
ToxinEraser™ Endotoxin Removal Resin	1.5 ml pre-packed column
Regeneration Buffer	125 ml
Equilibration Buffer	125 ml
Flow-Speed Control	1
Collection Tubes	1 bag (3 Tubes)
Tips (1 ml)	2 bags (6 Tips/bag)
Protocol	1

Product Information

Characteristics of ToxinEraser™ Endotoxin Removal Resin

Size	1.5 ml in pre-packed column
Binding Capacity	Up to 2,000,000 EU/ml resin
Ligand	Modified PMB (Polymixin B)
pH Stability	pH 5 -10
Support Matrix	4% cross-linked agarose, spherical beads
Mean Particle Size	90 μm
Storage	2°C to 8°C (Do not freeze.)
Equilibration Buffer	Phosphate-Buffer, pH 8.0
Regeneration Buffer	Sodium Phosphate-Buffer, pH 8.0; Triton-114
Types of substances that can be applied to the column	Purified recombinant proteins, peptides, antibodies, polysaccharides, etc.
Tolerable Ionic Strength	0.1 to 0.5 M NaCl
Tested reagents that do not interfere with performance	20% DMSO, 20% ethanol, 20% glycerol;1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT.

Storage

Regeneration and storage of the Column.
To regenerate the column, wash the column with 10 ml of equilibration buffer and allow the column to drain completely. Add ethanol to the regeneration buffer to a final concentration of 20%, adding at least 1.5 ml to the column for storage. Store at 2-8°C. Do not freeze.

For research and manufacturing use. Direct human use, including taking orally and injection are forbidden.

Specifications

More Information
SKU	GSCRPT-L00338
Supplier Part Number	L00338
UM	EA
UNSPSC	41105322
Manufacturer	GenScript USA Inc
Temperature	Regeneration and storage of the Column. To regenerate the column, wash the column with 10 ml of equilibration buffer and allow the column to drain completely. Add ethanol to the regeneration buffer to a final concentration of 20%, adding at least 1.5 ml t
ProductLine	GSCRPT
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	7
Hazardous	N
Energy Star	No
Green	No
Controlled	N

Provide Content Correction

NETA PART NO.	Quantity

GenScript Toxineraser™ Endotoxin Removal Kit; 1Kit

Product Title