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GenScript Monorab™ Anti-Evolocumab Antibody (36a11), Mab, Rabbit; 40ug
List Price
$205.00
Your Price
$205.00
GenScript Monorab™ Anti-Evolocumab Antibody (36a11), Mab, Rabbit - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART:
GSCRPT-A02294-40
MFG.PART:
A02294-40
UNSPSC:
12352203
Manufacturer:
GenScript USA Inc
Overview
| Specificity | This product is specific for Evolocumab. |
| Host Species | Rabbit |
| Immunogen | Evolocumab |
| Conjugate | Unconjugated |
Applications
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||
| |||||||||
Properties
| Form | Lyophilized |
| Storage Buffer | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification | Protein A affinity column |
| Isotype | Rabbit IgG, κ |
| Clonality | Monoclonal |
| Clone ID | 36A11 |
| Note | GenScript can customize this product per customers request including product size, buffer components, etc. |
Background
| Target Background | Evolocumab, also known as Repatha, is a monoclonal antibody used to treat hyperlipidemia through immunotherapy. This fully human monoclonal antibody works by blocking the activity of PCSK9, a protein responsible for breaking down LDL receptors. By inhibiting PCSK9, Repatha enhances the livers capacity to remove LDL-C, commonly referred to as "bad" cholesterol, from the bloodstream. Evolocumab is the second PCSK9 inhibitor on the market, first being alirocumab. |
| Synonyms | Evolocumab；Repatha；AMG 145；PCSK9 Inhibitor；AMG-145；GTPL7343 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-A02294-40 |
|---|---|
| Supplier Part Number | A02294-40 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| Temperature | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |