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Protein is expressed in E.coli. The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Description
Catalogue Number
GF327
Description
IL-15, Human Recombinant Animal Free
Alternate Names
Interleukin-15
IL15
Background Information
IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Recombinant human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.
Product Information
Presentation
Product is presented in 10 mM Sodium Phosphate, pH 8.5 and is filtered through a 0.2 micron filter before lyophilization.
Quality Level
MQ100
Biological Information
Purity
Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Source
Protein is expressed in E.coli. The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
UniProt Number
P40933
Product Usage Statements
Quality Assurance
The ED50 was determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.