Sigma-Aldrich Dpdpe - Cas 88373-73-3 - C

Assay

≥99% (HPLC)

Quality Level

100

Form

solid

Manufacturer/Tradename

Calbiochem^®

Storage Condition

OK to freeze
protect from light

Color

off-white

Solubility

water: 1 mg/mL

Storage Temp.

−20°C

Inchi

1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1

Inchi Key

MCMMCRYPQBNCPH-WMIMKTLMSA-N

General Description

A potent agonist selective for δ opioid receptor (EC₅₀= 5.2 nM). Exhibits anti-convulsant effectsin vivoin rats, also used in nociceptive studies.

Biochem/Physiol Actions

Primary Target
δ opioid receptor

Warning

Toxicity: Standard Handling (A)

Sequence

Tyr-D-Pen-Gly-Phe-D-Pen (2-5 disulfide bond)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chen, C., 1997.J. Pharmacol. Exp. Ther. 283,1151.
Chandrakumar, S., et al., 1992.J. Med. Chem. 35,2928.
Tortella, F. 1988.Peptides. 9,1177.
Clark, A., et al., 1986.Eur. J. Pharmacol. 128,303.CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany