Millipore Anti-Asc Mouse Ab, 100ug, 1mg/Ml, Monoclonal, 7.4

Millipore Anti-ASC Mouse Antibody, 100 ug Net Content, 1 mg/mL, Monoclonal, Mouse Host Species, Purified, Liquid Form, 7.4 pH, 2 to 8 deg C, 2EI-7 Clone, Mouse, Human Species Reactivity, IgG1 kappa Isotype. Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, Bcl10, Apaf-1, ARC, caspase-2 and caspase-9. A novel CARD domain containing protein has been identified in human and mouse and designated ASC and TMS1. Irregular expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells. Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues (Additional S&H or Hazmat Fees May Apply) - Mill