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Cayman Optineurin (C-Term) Monoclonal Antibody (Clone 8e12); Size
Cayman Optineurin (C-Term) Monoclonal Antibody (Clone 8e12); Size- 100 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$315.00
Your Price
$315.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-27230-100 |
MFG.PART: | 27230-100 |
UNSPSC: | 12352203 |
Manufacturer: | Cayman |
Product Description
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin (Item No. ), which is the inactive form of (–)-blebbistatin (Item No. ). Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications., The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3aR)- 1,2,3,3a- tetrahydro-3a -hydroxy-7- nitro-1- phenyl-4H- pyrrolo[2,3- b]quinolin-4- one
CAS Number
1217619-62-9
Synonyms
- R-
(−)- 7- Desmethyl- 8- nitro Blebbistatin
Molecular Formula
C17H13N3O4
Formula Weight
323.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
234, 270, 315, 350, 443 nm
SMILES
O=C1[C@]2(O)C(N(C3=CC=CC=C3)CC2)=NC4=C1C=CC([N+]([O-])=O)=C4
InChi Code
InChI=1S/C17H13N3O4/c21-15-13-7-6-12(20(23)24)10-14(13)18-16-17(15,22)8-9-19(16)11-4-2-1-3-5-11/h1-7,10,22H,8-9H2/t17-/m0/s1
InChi Key
VIMYHNYWFMRDKQ-KRWDZBQOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
SKU | CAYM-27230-100 |
---|---|
Supplier Part Number | 27230-100 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/27230m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |