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Genscript IFN-γ, Rat (CHO-expressed)
Genscript IFN-γ, Rat (CHO-expressed) - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$580.00
Your Price
$580.00
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NETA PART: | GSCRPT-Z02982-1 |
MFG.PART: | Z02982-1 |
UNSPSC: | 41106514 |
Manufacturer: | GenScript USA Inc |
Product Introduction
Species | Rat | |
Protein Construction |
| |
Purity | > 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC | |
Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
Biological Activity | ED50 < 2.5 ng/ml, measured by cytotoxicity assay using WEHI-279 cells, corresponding to a specific activity of > 4.0 × 105 units/mg. | |
Expression System | CHO | |
Apparent Molecular Weight | 15~25 kDa, on SDS-PAGE under non-reducing conditions. | |
Formulation | Lyophilized after extensive dialysis against PBS. | |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | |
Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
Target Background | Interferon-γ (IFN-γ), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The active form of IFN-γ is an antiparallel dimer that interacts with the receptor IFN-γR1 and sets off IFN-γ/JAK/STAT pathway. IFN-γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-γ–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers. |
Synonyms | Immune Interferon; type II interferon; T cell interferon; MAF; IFNG; IFG; IFI; IFN-gamma |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
SKU | GSCRPT-Z02982-1 |
---|---|
Supplier Part Number | Z02982-1 |
UM | EA |
UNSPSC | 41106514 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |