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AG Scientific Celastrol, 5 MG
AG Scientific Celastrol (5MG), also known as Tripterin, is a cell-permeable proteasome inhibitor. Celastrol acts as an antioxidant, anti-inflammatory & immunosuppressive agent (Additional S&H Or Hazmat Fees May Apply) - AG
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$79.61
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$79.61
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NETA PART: | RPI-C-2262-5MG |
MFG.PART: | C-2262-5MG |
UNSPSC: | 12352200 |
Manufacturer: | AG Scientific |
AG Scientific
Celastrol (also known as Tripterin) is a cell-permeable proteasome inhibitor. Celastrol acts as an antioxidant, anti-inflammatory and immunosuppressive agent. It suppresses LPS-induced cytokine release in macrophages and monocytes (IC= 40 nM for IL-1 and IL-1, 80 nM for IL-6, 110 nM for prostaglandin E2 and 210 nM for IL-8 and TNF).
Celastrol suppresses nitric oxide production (IC= 230 nM) and LPS-induced NF-B activation (IC= 270 nM). It inhibits chymotrypsin-like activity of 20S proteasome (IC= 2.5 M) and lipid peroxidation induced by ADP and Fe in rat liver mitochondria (IC= 7 M).
Isolated fromTripterygium wilfordii.
SKU | RPI-C-2262-5MG |
---|---|
Supplier Part Number | C-2262-5MG |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | AG Scientific |
MSDS URL | https://agscientific.com/system/product_documents/C-2262%2C%20Celastrol%2C%20SDS%202022_r02_1.pdf |
Temperature | -20°C |
Refrigerated-Frozen | Y |
CountryOfOrigin | China |
ProductLine | AG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 5.00 |
Lead Time | 5 Business Days |
Hazardous | N |
CAS Number | 34157-83-0 |