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Millipore Anti-Pp2a Antibody, A Subunit Detects Level Of Pp2a & Has Been Published & Validated For Use In Ip & Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
100mM triethylamine, 100mM sodium phosphate, 0.02% sodium azide before the addition of glycerol to 30%.
Quality Level
MQ100
Applications
Application
Anti-PP2A Antibody, A subunit detects level of PP2A & has been published & validated for use in IP & WB.
Key Applications
Immunoprecipitation
Western Blotting
Biological Information
Immunogen
KLH-conjugated, synthetic peptide of 13 amino acids (MAAADGDDSLY-Ahx-C), containing amino acids 1-11 of human PP2A, A subunit. Ahx is aminohexanoic acid. The immunizing sequence is conserved in human, mouse, rat, porcine and Xenopus.
Host
Rabbit
Specificity
PP2A A subunit, α isoform
Isotype
IgG
Species Reactivity
Human
Mouse
Pig
Rat
Xenopus
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_002716
Entrez Gene Summary
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene.
Gene Symbol
PPP2R1A
PP2A-A-alpha
PR65A
Purification Method
Immunoaffinity Chromatography
UniProt Number
P30153
Molecular Weight
63-65kDa
Product Usage Statements
Quality Assurance
Routinely evaluated by immunoblot on RIPA lysates from 3T3/A31 cells.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
