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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M, R | IP, WB, ICC | Rb | Serum | Polyclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | AB5779 |
| Brand Family | Chemicon® |
| Trade Name |
|
| Description | Anti-Striatin Antibody |
| Background Information | Striatin is found in all mammalian cells and may be involved in vesicular transport, dendrite growth and cellular signalling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also include SG2NA (striatin 3) and Zinedin (striatin 4). |
| Product Information | |
|---|---|
| Format | Serum |
| Presentation | Rabbit serum. Liquid containing 40% glycerol and 0.02% sodium azide. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-Striatin Antibody detects level of Striatin & has been published & validated for use in IP, WB & IC. |
| Key Applications |
|
| Application Notes | Western blot: 1:500-1:1,000. The antibody reacts with the ~110 kDa striatin protein in 293 cell lysate. Immunocytochemistry: 1:500 Immunoprecitation: 3 μL recommended as starting point. Optimal working dilutions must be determined by the end user. |
| Biological Information | |
|---|---|
| Immunogen | Synthetic Striatin peptide. |
| Host | Rabbit |
| Specificity | Reacts with Striatin. No cross reactivity with SG2NA. |
| Species Reactivity |
|
| Antibody Type | Polyclonal Antibody |
| Entrez Gene Number |
|
| Gene Symbol |
|
| UniProt Number |
|
| UniProt Summary | FUNCTION: SwissProt: O43815 # Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling. SIZE: 780 amino acids; 86132 Da SUBUNIT: Interacts with protein phosphatase 2A (PP2A) (Potential). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). TISSUE SPECIFICITY: Preferentially expressed in brain. SIMILARITY: SwissProt: O43815 ## Belongs to the WD repeat striatin family. & Contains 6 WD repeats. |
| Product Usage Statements | |
|---|---|
| Usage Statement |
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| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain at -20°C in undiluted for up to 12 months after date of receipt. For long-term storage, may be stored at -80°C. Avoid repeated freeze/thaw cycles at temperatures below -20°C. |
| Packaging Information | |
|---|---|
| Material Size | 100 µL |