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Millipore Active, Recombinant Full-Length Human Yes, Containing Additional N-Terminal His6 Tag, For Use In Kinase Assays. - Mill (Additional S&H or Hazmat Fees May Apply)
Recombinant full-length human Yes, containing additional N-terminal His6 tag
Product Information
Quality Level
MQ100
Applications
Application
Active, recombinant full-length human Yes, containing additional N-terminal His6 tag, for use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
Expressed by baculovirus in Sf21 cells
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_005433.3
Entrez Gene Summary
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
Gene Symbol
YES1
P61-YES
HsT441
Yes
c-yes
YES
p61-Yes
Protein Target
Yes
Purification Method
Ni2+/NTA-agarose
Target Sub-Family
TK
UniProt Number
P07947
UniProt Summary
FUNCTION: SwissProt: P07947 # Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46. SIZE: 543 amino acids; 60801 Da SUBCELLULAR LOCATION: Cytoplasm, cytosol. Note=In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies. PTM: Autophosphorylated. SIMILARITY: SwissProt: P07947 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight
63kDa
Product Usage Statements
Quality Assurance
routinely evaluated by phosphorylation of Poly (Glu4-Tyr) substrate
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
1 year at -70°C
Packaging Information
Material Size
10 µg
Material Package
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-478M when ordering the 250 µg size.
