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AG Scientific G-418 Sulfate, 5 G
AG Scientific G-418 Sulfate (5 G) is an aminoglycoside ATB that causes a chain of nonsense mutations during translation. G-418 binds to the 80S subunit of the ribosome by blocking the elongation phase of PRT synth (Addtl S&H Or Haz Fees May Apply) - AG
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$147.42
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$147.42
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NETA PART: | RPI-G-1033-5GM |
MFG.PART: | G-1033-5GM |
UNSPSC: | 51102800 |
Manufacturer: | AG Scientific |
AG Scientific
(Additional S&H Or Hazmat Fees May Apply) - AG
Description:
G-418 Sulfate is an aminoglycoside antibiotic that is synthesized from Micromonospora rhodorangea and functions by causing a chain of nonsense mutations during translation.
Due to translation G-418 inhibited polypeptide synthesis and protein elongation. G-418 binds to the 80S subunit of the ribosome by blocking the elongation phase of protein synthesis, both in prokaryotic and eukaryotic cells. It also shows activity against protozoa, cecal amoebiasis, and helminthes.
Applications:
- Used routinely in molecular genetics experiments for selecting eukaryotic transformants
- Used in plant and mammalian cell culture as a selectable marker
- Used as a gene selection antibiotic that has a powerful new role in genome editing, utilizing the CRISPR/CAS9 system.
- Ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro
(Additional S&H Or Hazmat Fees May Apply) - AG
SKU | RPI-G-1033-5GM |
---|---|
Supplier Part Number | G-1033-5GM |
UM | EA |
UNSPSC | 51102800 |
Manufacturer | AG Scientific |
MSDS URL | https://agscientific.com/system/product_documents/G-1033%2C%20G-418%20sulfate%2C%20SDS%202022_r01_3.pdf |
Temperature | 4°C |
Refrigerated-Frozen | Y |
CountryOfOrigin | Japan |
ProductLine | AG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 5.00 |
Lead Time | 5 Business Days |
Hazardous | N |
CAS Number | 108321-42-2 |