Takara IkappaBalpha Dominant-Negative Vector Set \Each

Takara Set of two vectors for studying NFκB and related signaling pathways. The pCMV-IκBα Vector expresses the wild-type IκBα protein. The pCMV-IκBαM Vector contains a mutated form of IκBα with a serine-to-alanine mutation at residues 32 and 36. This mutated form does not undergo signal-induced phosphorylation, and thus, remains bound to NFκB. Both genes are expressed from the constitutive CMV promoter.- TAKBGN (Additional S&H or Hazmat Fees May Apply)