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Cayman Apoptosis Activator 2; Purity- Greater Than Or Equal To 95
Cayman Apoptosis Activator 2; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$66.00
Your Price
$66.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-10004176-10 |
| MFG.PART: | 10004176-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Apoptosis activator 2 promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome, thus increasing procaspase-9 processing and subsequent caspase-3 activation. This compound has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 μM) with weak or no effect on normal cell lines or those lacking Apaf-1, caspase-9, or caspase-3 activity (IC50s > 40 μM).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(3,4-
CAS Number
79183-19-0
Synonyms
- AAII
- N-(3,4-dichlorobenzyl) Isatin
Molecular Formula
C15H9Cl2NO2
Formula Weight
306.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS(pH 7.2) (1:4): 0.25 mg/ml
- Ethanol: 1 mg/ml
λmax
245, 296 nm
SMILES
O=C1C(C2=CC=CC=C2N1CC3=CC=C(Cl)C(Cl)=C3)=O
InChi Code
InChI=1S/C15H9Cl2NO2/c16-11-6-5-9(7-12(11)17)8-18-13-4-2-1-3-10(13)14(19)15(18)20/h1-7H,8H2
InChi Key
KGRJPLRFGLMQMV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10004176-10 |
|---|---|
| Supplier Part Number | 10004176-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/10004176m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 79183-19-0 |