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Cayman Arachidonic Acid-D11
Cayman Arachidonic Acid-D11 - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$117.00
Your Price
$117.00
HOW MUCH YOU SAVE:
0.00 %
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NETA PART: | CAYM-10006758-500 |
MFG.PART: | 10006758-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
TNP-470 is a synthetic analog of fumagillin (Item No. ) that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2; IC50 = 2 µM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo.,, It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and microsporidiosis.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2- chloroacetyl)- carbamic acid, (3R,4S,5S,6R)- 5-methoxy-4- [(2R,3R)-2- methyl-3- (3-methyl-2- buten-1-yl)-2- oxiranyl]-1- oxaspiro[2.5] oct-6-yl ester
CAS Number
129298-91-5
Synonyms
- AGM-1470
- O-(Chloroacetyl-carbamoyl) Fumagillol
- NSC 642492
Molecular Formula
C19H28ClNO6
Formula Weight
401.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 10 mg/ml
SMILES
O=C(NC(CCl)=O)O[C@@H]1CC[C@@]2(OC2)[C@]([C@](O3)(C)[C@H]3C/C=C(C)/C)([H])[C@@H]1OC
InChi Code
InChI=1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)/t12-,13-,15-,16-,18+,19+/m1/s1
InChi Key
MSHZHSPISPJWHW-PVDLLORBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10006758-500 |
---|---|
Supplier Part Number | 10006758-500 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10006758m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 500 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 2692624-11-4 |