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Cayman 3-Thio-Pheneacrylic Acid; Purity- Greater Than 98%; Size-
NETA PART: | CAYM-10007103-10 |
MFG.PART: | 10007103-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities. It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 µM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid (Item No. ). It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 µM for DNA, RNA, and protein synthesis, respectively. In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS). It also increases calcium mobilization in platelets at concentrations ≥3 µM and induces platelet aggregation (EC50 = 8 µM).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name | (3α,4β)-3-hydroxy-urs-12-en-23-oic acid |
CAS Number | 631-69-6 |
Molecular Formula | C30H48O3 |
Formula Weight | 456.7 |
Purity | ≥95% |
Formulation | A crystalline solid |
Solubility |
|
SMILES | O[C@@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]1(C(O)=O)C |
InChi Code | InChI=1S/C30H48O3/c1-18-10-13-26(3)16-17-28(5)20(24(26)19(18)2)8-9-21-27(4)14-12-23(31)30(7,25(32)33)22(27)11-15-29(21,28)6/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21-,22-,23-,24+,26-,27-,28-,29-,30?/m1/s1 |
InChi Key | NBGQZFQREPIKMG-KPQZNPKPSA-N |
Origin | Plant/Boswellia serrata |
Storage | -20°C |
Shipping | Room Temperature in continental US; may vary elsewhere |
Stability | ≥ 2 years |
SKU | CAYM-10007103-10 |
---|---|
Supplier Part Number | 10007103-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10007103m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1195-52-4 |