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Cayman Palmitic Acid Methyl Ester; Purity- Greater Than Or Equal
NETA PART: | CAYM-10007358-1000 |
MFG.PART: | 10007358-1000 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
SMER28 is a small-molecule enhancer (SMER) of autophagy that increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntingtons, Parkinsons, and Alzheimers diseases.,, SMER28 induces clearance of amyloid-β (Aβ) peptides and the amyloid precursor protein c-terminal fragment (APP-CTF) in mouse embryonic fibroblasts (MEFs) isolated from wild-type, but not autophagy-related protein 5 knockout (Atg5-/-), mouse embryos in a concentration-dependent manner. It induces autophagy independently of rapamycin (Item No. ) in mammalian cells at a concentration of 47 µM. SMER28 also promotes reprogramming of fibroblasts into neural stem cells when used in combination with other chemical reagents.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 1 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
Shipping & Storage Information
SKU | CAYM-10007358-1000 |
---|---|
Supplier Part Number | 10007358-1000 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10007358m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1000 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 112-39-0 |