Cayman Leukotriene A4 Hydrolase (Human, Recombinant); Purity- Gre

Leukotriene A₄ hydrolase (LTA₄H) is a bifunctional zinc metalloenzyme that converts LTA₄ into LTB₄, a potent neutrophil chemoattractant. In addition to the hydrolase activity, LTA₄H also exhibits anion-dependent aminopeptidase activity.^, LTA₄H is a potential new drug target for a variety of indications associated with leukocyte infiltration to sites of inflammation. Cayman’s LTA₄H (human, recombinant) has been expressed and purified from E. coli. Both the epoxide hydrolase and aminopeptidase activities of the enzyme are functional as assessed by measurement of the separate enzyme activities. The enzyme therefore has application for the screening of inhibitors of LTB₄ synthesis.

WARNING This product is not for human or veterinary use.