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Cayman Leukotriene E4-D5; Purity- Greater Than Or Equal To 99% De
Cayman Leukotriene E4-D5; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D5); Size- 100 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
Leukotriene E4-d5 (LTE4-d5) contains five deuterium atoms at the 19, 19, 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTE4 by GC- or LC-mass spectrometry. LTE4 is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities characteristic of cysteinyl leukotrienes., Unlike LTC4 and LTD4, LTE4 accumulates in both plasma and urine. Therefore, urinary excretion of LTE4 is most often used as an indicator of asthma.,, In humans, basal levels of LTE4 range from 1-100 pg/mg creatinine. In asthmatic patients, urinary LTE4 levels increase to 80-1,000 pg/mg creatinine.
WARNING This product is not for human or veterinary use.