Cayman Cylindrospermopsin; Purity- Greater Than Or Equal To 95%;

Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC₅₀s = 1.3 and 2.4 µM, respectively), leading to cell death. It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a K_i value of 10 µM. Cylindrospermopsin is genotoxic, inducing DNA damage as evidenced by double strand breaks and reducing cell viability in HepG2 cells at 0.1-0.5 µg/ml.

WARNING This product is not for human or veterinary use.