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Cayman Zafirlukast; Purity- Greater Than Or Equal To 97%; Size- 1
Cayman Zafirlukast; Purity- Greater Than Or Equal To 97%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$19.00
Your Price
$19.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-10008282-10 |
| MFG.PART: | 10008282-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
β-Calcitonin gene-related peptide (β-CGRP) is a neuropeptide with roles in vasodilation, cardiovascular regulation, and inflammation. It belongs to the calcitonin family of peptides, which also includes α-CGRP (Item Nos. | ), amylin (Item No. ), calcitonin (Item Nos. | ), and adrenomedullin. β-CGRP binds selectively to a heteromeric complex of calcitonin receptor-like receptor (CRLR) and receptor activity-modifying protein 1 (RAMP1; IC50 = 0.01 nM) over a complex of CLCR and RAMP2 (IC50 = 300 nM). It binds to rat brain and spleen membrane preparations (IC50s = 1.1 and 1 nM, respectively) and relaxes human cerebral and middle meningeal arterial segments precontracted with prostaglandin F2α (PGF2α; Item No. ; IC50s = 0.38 and 4.9 nM, respectively)., In vivo, β-CGRP induces a 50% increase in diameter of arterioles precontracted with human endothelin-1 (ET-1; Item No. ) in hamster cheek pouch at a concentration of 15.8 pM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-L-
Synonyms
- Calcitonin Gene-Related Peptide-2 (human)
- β-Calcitonin Gene-Related Peptide (human)
- CGRP-2 (human)
Molecular Formula
C162H267N51O48S3 • XCF3COOH
Formula Weight
3793.4
Purity
≥95%
Formulation
A lyophilized powder
Solubility
- Water: 1 mg/ml
SMILES
NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CO)NC(CNC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@@]([C@@H](C)O)([H])NC([C@@H]1CCCN1C([C@H](C(C)C)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@@H](NC(CNC(CNC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(CNC([C@@H](NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](C(C)C)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CC(N)=O)N2)=O)=O)C)=O)=O)CSSC[C@H](NC([C@@H](N[H])C)=O)C2=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCSC)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)CC5=CC=CC=C5)=O.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C162H267N51O48S3.C2HF3O2/c1-74(2)53-98(186-118(227)65-178-130(231)82(16)182-139(240)99(54-75(3)4)193-135(236)94(43-34-49-175-161(170)171)188-142(243)102(58-91-62-174-73-181-91)198-158(259)127(88(22)221)212-155(256)122(79(11)12)207-151(252)111-72-264-263-71-110(203-129(230)81(15)165)150(251)197-104(60-114(167)223)146(247)210-124(85(19)218)156(257)184-84(18)132(233)209-125(86(20)219)159(260)204-111)140(241)194-100(55-76(5)6)141(242)202-108(69-216)148(249)190-95(44-35-50-176-162(172)173)137(238)200-106(67-214)133(234)179-63-116(225)177-64-117(226)185-96(46-52-262-23)138(239)206-121(78(9)10)154(255)191-93(42-31-33-48-164)136(237)201-109(70-217)149(250)196-103(59-113(166)222)143(244)195-101(57-90-39-28-25-29-40-90)144(245)208-123(80(13)14)160(261)213-51-36-45-112(213)152(253)211-126(87(21)220)157(258)199-105(61-115(168)224)145(246)205-120(77(7)8)153(254)180-66-119(228)187-107(68-215)147(248)189-92(41-30-32-47-163)134(235)183-83(17)131(232)192-97(128(169)229)56-89-37-26-24-27-38-89;3-2(4,5)1(6)7/h24-29,37-40,62,73-88,92-112,120-127,214-221H,30-36,41-61,63-72,163-165H2,1-23H3,(H2,166,222)(H2,167,223)(H2,168,224)(H2,169,229)(H,174,181)(H,177,225)(H,178,231)(H,179,234)(H,180,254)(H,182,240)(H,183,235)(H,184,257)(H,185,226)(H,186,227)(H,187,228)(H,188,243)(H,189,248)(H,190,249)(H,191,255)(H,192,232)(H,193,236)(H,194,241)(H,195,244)(H,196,250)(H,197,251)(H,198,259)(H,199,258)(H,200,238)(H,201,237)(H,202,242)(H,203,230)(H,204,260)(H,205,246)(H,206,239)(H,207,252)(H,208,245)(H,209,233)(H,210,247)(H,211,253)(H,212,256)(H4,170,171,175)(H4,172,173,176);(H,6,7)/t81-,82-,83-,84-,85+,86+,87+,88+,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,120-,121-,122-,123-,124-,125-,126-,127-;/m0./s1
InChi Key
GQLXFRMJBCXCCG-RYZBVDOXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10008282-10 |
|---|---|
| Supplier Part Number | 10008282-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/10008282m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 107753-78-6 |