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Cayman 11 Alphahydroxy Testosterone; Purity- Greater Than Or Eq
Cayman 11 Alpha -Hydroxy Testosterone; Purity- Greater Than Or Equal To 97%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$186.00
Your Price
$186.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-10008647-5 |
MFG.PART: | 10008647-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
GSK690693 is an ATP-competitive, pan-Akt kinase inhibitor with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively. It also inhibits other members of the AGC kinase family, including AMPK, DAPK3, PAKs, PKA, PKC, PKG, and PrkX (IC50 values range from 2-81 nM). By preventing the phosphorylation of downstream Akt substrates, GSK690693 has been shown to inhibit proliferation and to induce apoptosis in various human tumor cells in vitro and in xenografts in immunocompromised mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
CAS Number
937174-76-0
Molecular Formula
C21H27N7O3
Formula Weight
425.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml
- DMSO: 25 mg/ml
λmax
215, 250, 315 nm
SMILES
NC1=NON=C1C2=NC3=C(C#CC(C)(O)C)N=CC(OC[C@@H]4CNCCC4)=C3N2CC.Cl
InChi Code
InChI=1S/C21H27N7O3.ClH/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17;/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27);1H/t13-;/m0./s1
InChi Key
MUIKCMZJDWADGZ-ZOWNYOTGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10008647-5 |
---|---|
Supplier Part Number | 10008647-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10008647m.pdf |
Temperature | 4 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 426212 |