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Cayman Acid Phosphatase Stop Solution; Size- 1 Ea
NETA PART: | CAYM-10009148-1 |
MFG.PART: | 10009148-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Glutathione S-transferase 3 (GST3), also known as GST-Pi, is an enzyme that catalyzes the conjugation of glutathione (GSH) to the electrophilic center of various phase I toxic xenobiotic metabolites, facilitating their excretion by phase III membrane channels, transporters, and pumps. It functions as a homodimer, with each monomer containing an N-terminal GSH-binding domain and a C-terminal domain with a hydrophobic cavity (H-site) for toxic compound binding. GST3 is expressed primarily in erythrocytes, as well as in the brain, heart, lung, testis, skin, kidney, pancreas, and saliva. GST3 dimers can bind a nitric oxide (NO) carrier, such as S-nitrosoglutathione or dinitrosyl-diglutathionyl-iron complex (DNDGIC), with one active site, indicating a role in the storage and transport of NO, while maintaining detoxification activity in the second active site. Expression of GSTP1, the gene encoding GST3, is increased in patients with advanced-stage chronic kidney disease. GSTP1 polymorphisms are associated with increased risk of Parkinsons disease following exposure to cigarette smoke or pesticides, as well as with amyotrophic lateral sclerosis. Caymans GST3/GST-Pi (C-Term) Rabbit Monoclonal Antibody (Clone RM347) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.
WARNING This product is not for human or veterinary use.
Technical Information
- e-GST
- Glutathione-S-Transferase Pi-1
- GST3
- GST-Pi
- GSTP1-1
- (+) GST3
Shipping & Storage Information
SKU | CAYM-10009148-1 |
---|---|
Supplier Part Number | 10009148-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10009148m.pdf |
Temperature | 4 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |