We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Ldh Int (100x); Size- 1 Ea
Cayman Ldh Int (100x); Size- 1 Ea; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$20.00
Your Price
$20.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-10009328-1 |
| MFG.PART: | 10009328-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3., Obatoclax also induces autophagy in mouse embryo fibroblasts and in HeLa cells. This compound inhibits the growth of cancer cell lines and primary cancer isolates.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-
CAS Number
803712-79-0
Synonyms
- GX15-
070
Molecular Formula
C20H19N3O • CH3SO3H
Formula Weight
413.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMSO: 11 mg/ml
- Ethanol: 2 mg/ml
λmax
287, 314, 352, 546 nm
SMILES
CC(C=C(C)N1)=C1/C=C2C(OC)=CC(C(N3)=CC4=C3C=CC=C4)=N/2.CS(=O)(O)=O
InChi Code
InChI=1S/C20H19N3O.CH4O3S/c1-12-8-13(2)21-16(12)10-19-20(24-3)11-18(23-19)17-9-14-6-4-5-7-15(14)22-17;1-5(2,3)4/h4-11,21-22H,1-3H3;1H3,(H,2,3,4)/b19-10-;
InChi Key
ZFKXDVMHNXPEIY-PEZBNFGJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10009328-1 |
|---|---|
| Supplier Part Number | 10009328-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/10009328m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |