Cayman 17-Trifluoromethylphenyl Trinor Prostaglandin F2 Alpha Iso

Cayman 17-Trifluoromethylphenyl Trinor Prostaglandin F2 Alpha Isopropyl Ester; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)

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NETA PART:	CAYM-10010062-10
MFG.PART:	10010062-10
UNSPSC:	12352200
Manufacturer:	Cayman

Description

Product Description

Prostaglandin F_2α (PGF_2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.^1,2,3 17-trifluoromethylphenyl trinor PGF_2α is an analog of PGF_2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF_2α isopropyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF_2α. Isopropyl esters of PGs can serve as prodrugs, as they can be efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

9α,11α,15S-trihydroxy-17-trifluoromethyl-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester

Synonyms

17-trifluoromethylphenyl trinor PGF_2α isopropyl ester

Molecular Formula

C₂₇H₃₇F₃O₅

Formula Weight

498.6

Purity

≥98%

Formulation(Request formulation change)

A solution in ethanol

Solubility(Learn about Variance in Solubility)

DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 50 mg/ml
Ethanol:PBS(pH 7.2) (1:5): 0.2 mg/ml

SMILES

O[C@@H](CCC1=CC=CC(C(F)(F)F)=C1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(OC(C)C)=O

InChi Code

InChI=1S/C27H37F3O5/c1-18(2)35-26(34)11-6-4-3-5-10-22-23(25(33)17-24(22)32)15-14-21(31)13-12-19-8-7-9-20(16-19)27(28,29)30/h3,5,7-9,14-16,18,21-25,31-33H,4,6,10-13,17H2,1-2H3/b5-3-,15-14+/t21-,22+,23+,24-,25+/m0/s1

InChi Key

SLQVIHUQICCVQY-KEQMOKKCSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 2 years

Specifications

More Information
SKU	CAYM-10010062-10
Supplier Part Number	10010062-10
UM	UNIT
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	https://www.caymanchem.com/msdss/10010062m.pdf
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	US
ProductLine	CAYM
Qty	10
MinOrderQty	1
Weight	7.00
Lead Time	2 Business Days
Hazardous	Y

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Cayman 17-Trifluoromethylphenyl Trinor Prostaglandin F2 Alpha Iso

Product Description

Technical Information

Shipping & Storage Information

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