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Cayman Prostaglandin D2-D9; Purity- Greater Than Or Equal To 99%
Cayman Prostaglandin D2-D9; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D9); Size- 25 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$79.00
Your Price
$79.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-10010123-25 |
MFG.PART: | 10010123-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Rosuvastatin-d6 is intended for use as an internal standard for the quantification of rosuvastatin (Item Nos. | ) by GC- or LC-MS. Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the area of aortic atherosclerotic lesions in the same model. Formulations containing rosuvastatin have been used in the treatment of dyslipidemias.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R,5S,E)-7- (4-(4-fluoro phenyl)-2-(N- methylmethyl sulfonamido)- 6-(propan-2- yl- 1,1,1,3,3,3- d6)pyrimidin- 5-yl)-3,5- dihydroxyhept -6-enoate, monosodium salt
CAS Number
2070009-41-3
Molecular Formula
C22H21D6FN3O6S • Na
Formula Weight
509.6
Purity
≥98%
Formulation
A solid
Solubility
- Methanol: Soluble
SMILES
O[C@@H](C[C@H](CC([O-])=O)O)/C=C/C(C(C1=CC=C(F)C=C1)=NC(N(C)[S](C)(=O)=O)=N2)=C2C(C([2H])([2H])[2H])C([2H])([2H])[2H].[Na+]
InChi Code
InChI=1S/C22H28FN3O6S.Na/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;+1/p-1/b10-9+;/t16-,17-;/m1./s1/i1D3,2D3;
InChi Key
RGEBGDYYHAFODH-HPECXWNWSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10010123-25 |
---|---|
Supplier Part Number | 10010123-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10010123m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |