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Cayman Sirt1 Direct Assay Buffer (10x); Size- 1 Ea
NETA PART: | CAYM-10010993-1 |
MFG.PART: | 10010993-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
α,β-Methyleneadenosine 5-triphosphate (αβ-methylene ATP) is a phosphonic analog of ATP that is characterized by the replacement of the bridging oxygen atom between the α- and β-phosphate groups with methylene. It is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 µM) and is ~1,000-fold less potent at P2X2, P2X receptors 4-7, and P2Y receptors.,,, Persistent activation of purinoceptors results in desensitization, resulting in an antagonist-like effect of αβ-methylene ATP. αβ-methylene ATP is used as a stable analog of ATP (Item No. ) to study the interaction of ATP with kinases and other proteins., It weakly binds and inhibits adenylate cyclase in a calcium-dependent manner (Ki= ~0.5 mM).,
WARNING This product is not for human or veterinary use.
Technical Information
- αβ-methylene ATP
- PBS (pH 7.2): 10 mg/ml
Shipping & Storage Information
SKU | CAYM-10010993-1 |
---|---|
Supplier Part Number | 10010993-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10010993m.pdf |
Temperature | -80 |
Refrigerated-Frozen | Frozen |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |