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Cayman 15(R)-Iloprost; Purity- Greater Than Or Equal To 97%; Size
NETA PART: | CAYM-10043-5 |
MFG.PART: | 10043-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
R-568 is a calcimimetic and positive allosteric modulator of the calcium-sensing receptor (CaSR). It potentiates extracellular calcium-induced increases in intracellular calcium release and inhibits the secretion of parathyroid hormone (PTH; IC50 = 27 nM) in bovine parathyroid cells. R-568 decreases PTH and plasma calcium levels in rats (ED50s = 1.1 and 10.4 mg/kg, respectively). It suppresses parathyroid cell proliferation in a rat model of chronic renal insufficiency when administered at a dose of 15 mg/kg. Formulations containing R-568 have been used in the treatment of osteoporosis in post-menopausal women.
WARNING This product is not for human or veterinary use.
Technical Information
- KRN 568
- NPS R-568
- Tecalcet
- DMF: 5 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 10 mg/ml
- PBS (pH 7.2): 5 mg/ml
Shipping & Storage Information
SKU | CAYM-10043-5 |
---|---|
Supplier Part Number | 10043-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10043m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 85026-51-3 |