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Cayman 15(R)-Iloprost; Purity- Greater Than Or Equal To 97%; Size
Cayman 15(R)-Iloprost; Purity- Greater Than Or Equal To 97%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$109.00
Your Price
$109.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-10043-500 |
| MFG.PART: | 10043-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PACMA 31 is an irreversible inhibitor of protein disulfide isomerase (PDI; IC50 = 10 µM), an endoplasmic reticulum chaperone protein that catalyzes disulfide bond breakage, formation, and rearrangement. It inhibits PDI chaperone activity in a concentration- and time-dependent manner in an insulin aggregation assay and is cytotoxic to OVCAR-8 and OVCAR-3 ovarian cancer cells (IC50s = 0.9 and 0.32 µM, respectively). PACMA 31 binds to GPX4 and induces ferroptosis in OVCAR-8 and HT-1080 fibrosarcoma cells., It also reduces tumor growth in an OVCAR-8 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2,4-
CAS Number
1401089-31-3
Molecular Formula
C21H22N2O6S
Formula Weight
430.5
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 100 mM
SMILES
O=C(N(C(C1=CC=CS1)C(NCC(OCC)=O)=O)C2=CC=C(C=C2OC)OC)C#C
InChi Code
InChI=1S/C21H22N2O6S/c1-5-18(24)23(15-10-9-14(27-3)12-16(15)28-4)20(17-8-7-11-30-17)21(26)22-13-19(25)29-6-2/h1,7-12,20H,6,13H2,2-4H3,(H,22,26)
InChi Key
AHOOZADJPNUFOQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10043-500 |
|---|---|
| Supplier Part Number | 10043-500 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/10043m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 500 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 85026-51-3 |