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Cayman (S)-Am1241; Purity- Greater Than Or Equal To 98%; Size- 1
NETA PART: | CAYM-10490-1 |
MFG.PART: | 10490-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
(S)-AM1241 binds to cannabinoid (CB) receptors and is selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively, in a membrane assay using human receptors). (S)-1241 acts as an agonist at human, rat, and mouse CB2 receptors but shows greater activity at human CB2 (EC50 = 131 nM) than at rat and mouse CB2 receptors (EC50 = 785 and 2,000 nM, respectively). Similar to the racemate AM1241 (Item No. ), (S)-AM1241 produces antinociception to thermal, but not mechanical, pain in rats. The pain-reducing effect of (S)-AM1241 is blocked by the CB2-specific inhibitor SR 144528 (Item No. ) but not by either the CB1-selective inhibitor rimonabant (Item No. ) or the opioid receptor blocker naloxone (Item No. | ).
WARNING This product is not for human or veterinary use.
Technical Information
- (−)-
AM1241
- DMF: 25 mg/ml
- DMF:PBS(pH7.2) (1:2): 0.3 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 5 mg/ml
Shipping & Storage Information
SKU | CAYM-10490-1 |
---|---|
Supplier Part Number | 10490-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10490m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 444912-53-2 |