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Cayman (R)-Am1241; Purity- Greater Than Or Equal To 98%; Size- 10
NETA PART: | CAYM-10491-10 |
MFG.PART: | 10491-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Methyllysine (Kme) recognition “reader” domains play a central role in epigenetic regulation during cellular differentiation, development, and gene transcription. UNC1215 is a potent and selective chemical probe for the Kme reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. UNC1215 binds L3MBTL3 with a Kd value of 120 nM (IC50 = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. This probe is greater than 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined. See the website for more information.
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 16 mg/ml
- DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml
- DMSO: 5 mg/ml
- Ethanol: 14 mg/ml
Shipping & Storage Information
SKU | CAYM-10491-10 |
---|---|
Supplier Part Number | 10491-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10491m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 444912-51-0 |