We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Lp-533401; Purity- Greater Than Or Equal To 98%; Size- 5 M
Cayman Lp-533401; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$308.00
Your Price
$308.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-10492-5 |
MFG.PART: | 10492-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Casein kinase 2 (CK2) is a kinase with many targets and diverse roles in cell signaling and disease., TBCA is a selective, cell-permeable inhibitor of CK2 (IC50 = 0.11 µM, Ki = 77 nM) that has minimal effect on a panel of 28 other kinases. It induces cell death in Jurkat adult T cell leukemia cells (DC50 = 7.7 µM), driving caspase-dependent degradation of poly-ADP ribose polymerase while inhibiting CK2 activity. TBCA also supports a role for CK2 in platelet function and Akt phosphorylation but not protein splicing.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2E)-3- (2,3,4,5- tetrabromo phenyl)-2- propenoic acid
CAS Number
934358-00-6
Synonyms
- Casein Kinase II Inhibitor III
- Tetrabromocinnamic Acid
Molecular Formula
C9H4Br4O2
Formula Weight
463.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 1 mg/ml
λmax
237, 278 nm
SMILES
BrC1=C(Br)C(Br)=C(Br)C=C1/C=C/C(O)=O
InChi Code
InChI=1S/C9H4Br4O2/c10-5-3-4(1-2-6(14)15)7(11)9(13)8(5)12/h1-3H,(H,14,15)/b2-1+
InChi Key
SVJQCVOKYJWUBC-OWOJBTEDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-10492-5 |
---|---|
Supplier Part Number | 10492-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10492m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 945976-43-2 |