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Cayman Ha-130; Purity- Greater Than Or Equal To 98%; Size- 5 Mg;
NETA PART: | CAYM-10498-5 |
MFG.PART: | 10498-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Phenelzine is an inhibitor of monoamine oxidase (MAO; IC50 = 0.9 μM using rat brain mitochondrial preparations). It potentiates the effects of tryptamine on isolated rat fundus (EC50 = 90 nM) and increases tryptamine toxicity in mice with LD50 values of 85 and 500 mg/kg in the presence and absence of phenelzine, respectively. Phenelzine (20 mg/kg) increases GABA, dopamine, serotonin (5-HT; Item No. ), and norepinephrine levels in the hippocampus and cortex of socially isolated rats and rats treated with the NMDA receptor antagonist (+)-MK-801 (Item No. ). It also increases 5-HT levels in the ventral horn of the spinal cord, improves gross motor ability in a rotarod test, and increases locomotor activity in an open field test in mice with experimental autoimmune encephalomyelitis when administered at a dose of 30 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 170957
- W-1544A
- DMSO: Slightly Soluble
- Water: Slightly Soluble
Shipping & Storage Information
SKU | CAYM-10498-5 |
---|---|
Supplier Part Number | 10498-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/10498m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1229652-21-4 |