Cayman Hc Toxin; Purity- Greater Than Or Equal To 95%; Size- 500

Cayman Hc Toxin; Purity- Greater Than Or Equal To 95%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)

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NETA PART:	CAYM-10576-500
MFG.PART:	10576-500
UNSPSC:	12352200
Manufacturer:	Cayman

Description

Product Description

HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC₅₀ = 30 nM).^1,2 Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells.^3,4 HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.⁵

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

(6R,9S,14aR)-3,6R-dimethyl-9S-(6-((S)-oxiran-2-yl)-6-oxohexyl)decahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetranone

CAS Number

83209-65-8

Synonyms

Toxin I (Helminthosporium carbonum)

Molecular Formula

C₂₁H₃₂N₄O₆

Formula Weight

436.5

Purity

≥95%

Formulation(Request formulation change)

A crystalline solid

Solubility(Learn about Variance in Solubility)

DMSO: 10 mg/ml
Methanol: 10 mg/ml

λ_max

232 nm

SMILES

[H][C@@]12C(N([H])[C@@H](C)C(N([H])[C@H](C)C(N([H])[C@](CCCCCC([C@@H]3CO3)=O)([H])C(N1CCC2)=O)=O)=O)=O

InChi Code

InChI=1S/C21H32N4O6/c1-12-18(27)22-13(2)19(28)24-14(7-4-3-5-9-16(26)17-11-31-17)21(30)25-10-6-8-15(25)20(29)23-12/h12-15,17H,3-11H2,1-2H3,(H,22,27)(H,23,29)(H,24,28)/t12-,13+,14-,15+,17-/m0/s1

InChi Key

GNYCTMYOHGBSBI-SVZOTFJBSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-10576-500
Supplier Part Number	10576-500
UM	UNIT
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	https://www.caymanchem.com/msdss/10576m.pdf
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	US
ProductLine	CAYM
Qty	500
MinOrderQty	1
Weight	7.00
Lead Time	2 Business Days
Hazardous	Y
CAS Number	83209-65-8

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Cayman Hc Toxin; Purity- Greater Than Or Equal To 95%; Size- 500

Product Description

Technical Information

Shipping & Storage Information

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