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Cayman 16(R)-Afp 07 (Free Acid); Purity- Greater Than Or Equal To
Cayman 16(R)-Afp 07 (Free Acid); Purity- Greater Than Or Equal To 98%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$275.00
Your Price
$275.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-10991-500 |
| MFG.PART: | 10991-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM).1 AFP 07 shows weaker affinity for EP receptors, with Ki values > 100 nM for EP1-3 and > 10 nM for EP4.1,2 16(R)-AFP 07 is an epimer of AFP 07. Its biological properties, particularly through the IP and EP receptors, remain to be evaluated.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5Z-[3aR,3-
CAS Number
773825-80-2
Molecular Formula
C22H30F2O5
Formula Weight
412.5
Purity
≥98%
Formulation(Request formulation change)
A solution in methyl acetate
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 30 mg/ml
- PBS (pH 7.2): 1 mg/ml
SMILES
O[C@@H]([C@H](C)CC#CCC)/C=C/[C@H]1[C@H](O)C[C@H]2[C@@H]1C(F)(F)/C(O2)=C\CCCC(O)=O
InChi Code
InChI=1S/C22H30F2O5/c1-3-4-5-8-14(2)16(25)12-11-15-17(26)13-18-21(15)22(23,24)19(29-18)9-6-7-10-20(27)28/h9,11-12,14-18,21,25-26H,3,6-8,10,13H2,1-2H3,(H,27,28)/b12-11+,19-9+/t14-,15+,16-,17-,18+,21-/m1/s1
InChi Key
PVHIRYQSPDZLLG-HWMGRDFZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-10991-500 |
|---|---|
| Supplier Part Number | 10991-500 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/10991m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 500 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 773825-80-2 |