Cayman Forskolin; Purity- Greater Than Or Equal To 98%; Size- 10

Cyclic AMP (cAMP) is an important signal carrier necessary for the proper biological response of cells to hormones, neurotransmitters, and other extracellular signals. Forskolin is a naturally occurring diterpene that is produced by the Indian Coleus plant (C. forskohlii).¹ It directly activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations.² Forskolin binds to adenylyl cyclase in membranes from stably transfected Sf9 cells expressing type 1 adenylyl cyclase with an IC₅₀ value of 41 nM and demonstrates an EC₅₀ value of 0.5 μM in an activation assay assessing formation of cAMP from ATP.¹ Forskolin also interacts with glucose transporters and certain ion channels and has been used for examining adenylyl cyclase expression, regulation, and G protein signaling.²

WARNING This product is not for human or veterinary use.