We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Concanamycin A; Purity- Greater Than Or Equal To 95%; Size
Cayman Concanamycin A; Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$286.00
Your Price
$286.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-11050-1 |
| MFG.PART: | 11050-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Concanamycin A is a plecomacrolide antibiotic that has been found in Streptomyces. It is active against S. cerevisiae, S. sake, A. citri, P. citrinum, and P. oryzae (MICs = <0.39, <0.39, <0.39, 1.56, and 25 μg/ml, respectively). Concanamycin A inhibits vacuolar H+-ATPase (V-ATPase; EC50 = ~2.1-2.3 μM). It also decreases perforin levels in CD8+ OE4 cytotoxic T lymphocytes (CTLs). Concanamycin A (100 μM) inhibits concanavalin A-induced thymidine incorporation by 99% in isolated mouse splenic lymphocytes. It also prevents influenza virus entry into MDCK cells when used at a concentration of 0.8 μM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3Z,5E,7R,8R,
CAS Number
80890-47-7
Synonyms
- Antibiotic X 4357B
- NSC 674620
- X 4357B
Molecular Formula
C46H75NO14
Formula Weight
866.1
Purity
≥95%
Formulation
A solution in acetonitrile
Solubility
- Acetonitrile: Soluble
- DMSO: Soluble
- Methanol: Soluble
SMILES
C[C@H](/C=C(C)/C=C1\OC)[C@@H](O)[C@@H](CC)[C@@H](O)[C@H](C)C/C(C)=C\C=C\[C@H](OC)[C@@]([C@@H](C)[C@@H](O)[C@H](C)[C@@](O)(C[C@@H](O[C@@]2([H])C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O2)[C@@H]3C)O[C@@H]3/C=C/C)([H])OC1=O
InChi Code
InChI=1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22
InChi Key
DJZCTUVALDDONK-LNFFOTJESA-N
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-11050-1 |
|---|---|
| Supplier Part Number | 11050-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/11050m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 80890-47-7 |