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Cayman Brd4 Bromodomains 1 And 2 (Human, Recombinant; Aa 49-460)
Cayman Brd4 Bromodomains 1 And 2 (Human, Recombinant; Aa 49-460); Purity- Greater Than Or Equal To 70% Estimated By Sds-Page; Size- 100 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$364.00
Your Price
$364.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-11052-100 |
| MFG.PART: | 11052-100 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma., PMX-205 is also brain penetrant and reduces neuroinflammation and neurodegeneration in an animal model of Alzheimer’s disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N2-(1-oxo-3-
Molecular Formula
C45H62N10O6 • XCF3COOH
Formula Weight
839.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:6): 0.14mg/ml
λmax
219, 281 nm
SMILES
O=C([C@]([H])(CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3CCCCC3)NC([C@]4(N5CCC4)[H])=O)=O)N[C@@H](CCCNC(N)=N)C(NCCC[C@@]([H])(C5=O)NC(CCC6=CC=CC=C6)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C45H62N10O6.C2HF3O2/c46-45(47)49-24-9-18-34-40(57)48-23-10-19-35(51-39(56)22-21-29-12-3-1-4-13-29)44(61)55-25-11-20-38(55)43(60)54-36(26-30-14-5-2-6-15-30)41(58)53-37(42(59)52-34)27-31-28-50-33-17-8-7-16-32(31)33;3-2(4,5)1(6)7/h1,3-4,7-8,12-13,16-17,28,30,34-38,50H,2,5-6,9-11,14-15,18-27H2,(H,48,57)(H,51,56)(H,52,59)(H,53,58)(H,54,60)(H4,46,47,49);(H,6,7)/t34-,35-,36+,37-,38-;/m0./s1
InChi Key
JPQOMEWKZCTQMA-AZRFDLDXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11052-100 |
|---|---|
| Supplier Part Number | 11052-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/11052m.pdf |
| Temperature | -80 |
| Refrigerated-Frozen | Frozen |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |