We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman 4-Amino Benzamidoxime; Purity- Greater Than Or Equal To 97
NETA PART: | CAYM-11053-500 |
MFG.PART: | 11053-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. ) and docosahexaenoic acid (DHA; Item No. ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1; Item No. ) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase. 17(R)-RvD1 is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-RvD1 exhibits a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with maximal inhibition of ~35% at a 100 ng dose. In contrast to RvD1, the aspirin-triggered form resists rapid inactivation by eicosanoid oxidoreductases.
WARNING This product is not for human or veterinary use.
Technical Information
- Aspirin-triggered Resolvin D1
- AT-RvD1
- 17-epi-Resolvin D1
- 17(R)-RvD1
- DMF: 50 mg/ml
- Ethanol: 50 mg/ml
- PBS (pH 7.2): 0.05 mg/ml
Shipping & Storage Information
SKU | CAYM-11053-500 |
---|---|
Supplier Part Number | 11053-500 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11053m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | IN |
ProductLine | CAYM |
Qty | 500 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 277319-62-7 |