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Cayman Ethyl 4-Methyl-2-(2-Thienyl)-Thiazole-5 Carboxylate; Purit
NETA PART: | CAYM-11056-500 |
MFG.PART: | 11056-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
CpdA is a non-steroidal selective glucocorticoid receptor modulator. It is an aziridine precursor that can infiltrate cells and is translocated to the nucleus., It inhibits glucocorticoid receptor dimerization, which prevents transcription of gene targets such as NF-κB and subsequent cytokines through transrepression. Studies have shown contradictory results for binding affinity of CpdA compared with dexamethasone (Item No. ) that were either higher (4-fold, IC50 = 6.4 nM and 25.9 nM, respectively, in L929sA cells) or lower (63-fold, Kd = 81.8 nM and 1.29 nM, respectively, in BWTG3 cells) in whole cell binding assays.,
WARNING This product is not for human or veterinary use.
Technical Information
- Compound A
- DMF: 5 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 1 mg/ml
- PBS (pH 7.2): 10 mg/ml
Shipping & Storage Information
SKU | CAYM-11056-500 |
---|---|
Supplier Part Number | 11056-500 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11056m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | IN |
ProductLine | CAYM |
Qty | 500 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 56421-62-6 |